What is PGD?

Which diseases can be screened for?

PGD has been employed before to screen for the most common hereditary disorders. In most cases, preliminary genetic testing takes three to six months to complete. Prospective parents will receive information on any conditions not listed above during their first consultation.

PGD is utilised to screen for common hereditary diseases, like

  1. Huntington disease
  2. Hereditary breast cancer and ovarian carcinoma
  3. Myotonic dystrophy type I (Steinert disease)
  4. Familial Adenomatous Polyposis of the colon (FAP)
  5. Marfan syndrome
  6. Neurofibromatosis type I
  7. Cystic fibrosis
  8. Spinal muscular atrophy
  9. Fragile X syndrome
  10. Haemophilia A/B
  11. Duchenne muscular dystrophy
  12. Chromosome abnormalities (where one of the parents carries the abnormality, e.g. translocation, where two or more chromosomes show an abnormal structure)

If a prospective parent carries the gene for a hereditary disorder, his or her health situation will be further investigated, and the safety of an IVF procedure will be assessed. If the affected party is female, she will be examined by a gynaecologist and possibly by other medical specialists to determine whether it will be safe for her to become pregnant.